Colozo 145 mcg capsules, which contain the active ingredient Linaclotide, are a prescription medication primarily used to manage specific gastrointestinal conditions in adults. Primary Uses Chronic Idiopathic Constipation (CIC): It is used for adults who experience long-term, ongoing constipation without a known physical cause. Irritable Bowel Syndrome with Constipation (IBS-C): It helps treat adults suffering from IBS where constipation is the main symptom, often accompanied by abdominal pain and bloating.