Crisbo (Crisaborole) Ointment 2% w/w is a non-steroidal medication primarily used for the topical treatment of mild-to-moderate atopic dermatitis (eczema). It is approved for use in adults and children as young as 3 months old. Primary Uses and Benefits Reduces Inflammation: It contains a phosphodiesterase 4 (PDE4) inhibitor that suppresses the immune response causing redness and swelling. Relieves Itching: It helps break the “itch-scratch cycle“ by calming the skin, often providing relief within a few days. Steroid-Free Alternative: Unlike topical corticosteroids, it does not cause skin thinning, making it suitable for sensitive areas like the face or skin folds.