Adaferin (Adapalene Gel 0.1%) is a topical retinoid primarily used for the treatment of acne vulgaris. It works by modulating skin cell turnover and reducing inflammation to clear existing breakouts and prevent new ones from forming
Tretinoin, also known as all-trans retinoic acid (CAATRA), is medication used for the treatment of acne and acute promyelocytic leukemia. For acne it is applied to the skin as a cream or ointment. For leukemia it is taken by mouth for up to three months.